The Norte Grande (Big North, Far North) is one of the five natural regions into which CORFO divided continental Chile in 1950. It borders Peru to the north, the Pacific Ocean to the west, the Altiplano, Bolivia and Argentina to the east, and the Copiapó River to the south, beyond which lies the Norte Chico natural region.
The Norte Grande, which extends from the Peruvian border to about 27° south latitude, a line roughly paralleled by the Copiapó river, is extremely arid. It contains the Atacama Desert, one of the driest areas in the world; in certain sections, this desert does not register any rainfall at all. Average monthly temperatures range at sea level between about 20.5 °C during the summer and about 14 °C during the winter. Most of the population lives in the coastal area, where the temperatures are more moderate and the humidity higher.
The desert region is an elevated arid plateau descending gradually from the Andes towards the coast, where it breaks down abruptly from elevations of 800 to 1500 ft. From the sea this plateau escarpment has the appearance of a range of flat topped hills closely following the coast line. This topography generates coastal microclimates because the fog that frequently forms over the cold ocean waters, as well as any low clouds, is trapped by the high bluffs. This airborne moisture condenses in the spines and leaves of the vegetation, droplets that fall to the ground and irrigate the plants' roots. The fog of this area is known locally as Camanchaca.
Beyond the coastal bluffs, there is an area of rolling hills that encompasses the driest desert land; this area ends to the east with the Andes towering over it. This region is rainless, barren and inhospitable, absolutely destitute of vegetation except in some small river valleys where irrigation is possible, and on the slopes of some of the snow-covered peaks where the water from the melting snows nourishes a scanty and coarse vegetation before it disappears in the thirsty sands. It is very rich in mineral and saline deposits, however. This area is broken by ranges of barren hills having the appearance of spurs from the Andes, and by irregular lateral ranges in the vicinity of the main cordillera enclosing elevated saline plateaus. Within the mountain ranges parallel to the main chain of the Andes, the main one is the Cordillera Domeyko and among the salt flats the greater is the Salar de Atacama.