Mineralocorticoid receptor

NR3C2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Y9R, 1YA3, 2A3I, 2AA2, 2AA5, 2AA6, 2AA7, 2AAX, 2AB2, 2ABI, 2OAX, 3VHU, 3VHV, 3WFF, 3WFG, 4PF3, 4TNT, 4UDB, 4UDA, 5HCV
Identifiers
Aliases	NR3C2, MCR, MLR, MR, NR3C2VIT, nuclear receptor subfamily 3 group C member 2
External IDs	MGI: 99459 HomoloGene: 121495 GeneCards: NR3C2
Targeted by Drug
aldosterone, hydrocortisone, desoxycortone, dexamethasone, fludrocortisone, prednisolone, progesterone, drospirenone, finerenone, nimodipine, spironolactone
Gene ontology Molecular function • sequence-specific DNA binding • DNA binding • transcription factor activity, sequence-specific DNA binding • zinc ion binding • metal ion binding • steroid hormone receptor activity • steroid binding • protein binding • lipid binding Cellular component • cytoplasm • endoplasmic reticulum membrane • membrane • receptor complex • endoplasmic reticulum • nucleus • nucleoplasm Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • transcription initiation from RNA polymerase II promoter • signal transduction • steroid hormone mediated signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4306	110784
Ensembl	ENSG00000151623	ENSMUSG00000031618
UniProt	P08235	Q8VII8
RefSeq (mRNA)	NM_000901 NM_001166104	NM_001083906
RefSeq (protein)	NP_000892 NP_001159576	n/a
Location (UCSC)	Chr 4: 148.08 – 148.44 Mb	Chr 8: 76.9 – 77.25 Mb
PubMed search

1Y9R, 1YA3, 2A3I, 2AA2, 2AA5, 2AA6, 2AA7, 2AAX, 2AB2, 2ABI, 2OAX, 3VHU, 3VHV, 3WFF, 3WFG, 4PF3, 4TNT, 4UDB, 4UDA, 5HCV

4306

110784

ENSG00000151623

ENSMUSG00000031618

...
Wikipedia