The Ligier JS25 was a Formula One car designed by Michel Beaujon and Claude Galopin for use by the Ligier team during the 1985 Formula One season. Like its predecessor, the JS23, the JS25 was powered by a turbocharged Renault V6 engine although the car ran on Pirelli instead of Michelin tyres after the French company pulled out of Grand Prix racing at the end of 1984. Drivers of the car were initially their 1984 driver Andrea de Cesaris and veteran Jacques Laffite who returned to the team after two fruitless years at Williams, but after a series of crashes, de Cesaris was fired by team boss Guy Ligier and replaced by Philippe Streiff.

Using the JS25, the French team were able to score 23 points in 1985 and finished 6th in the Constructors Championship. Laffite was able to score two 3rd-place finishes and also a 2nd place at the season ending Australian Grand Prix where team mate Streiff also managed to finish 3rd, although his efforts to take 2nd from Laffite almost cause both cars to not finish the race. Streiff made contact with Laffite on the penultimate lap of the race and drove the last with his left front wheel almost off the car.

Easily the most spectacular moment for the JS25 came at the Austrian Grand Prix when de Cesaris (aptly nicknamed "de Crasheris") destroyed his car in a high-speed rollover on lap 14. The team had not yet seen the accident on the television monitors when de Cesaris returned to the pits and he merely told them that the car had stalled and could not restart it, causing the team to be shocked when they finally saw the crash on replay. It was after this event that team owner Guy Ligier decided he could no longer afford the repair bills for de Cesaris's frequent crashes, stating "I can no longer afford to employ this man" (this was despite the Italian's personal sponsor Marlboro paying the bulk of his salary). He was replaced by Streiff after the next race in the Netherlands.

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