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Latent TGF-beta binding protein

latent transforming growth factor beta binding protein 1
Identifiers
Symbol LTBP1
Alt. symbols TGF-beta1-BP-1
Entrez 4052
HUGO 6714
OMIM 150390
RefSeq NM_206943
UniProt Q14766
Other data
Locus Chr. 2 p22-p21
latent transforming growth factor beta binding protein 2
Identifiers
Symbol LTBP2
Alt. symbols LTBP3, C14orf141
Entrez 4053
HUGO 6715
OMIM 602091
RefSeq NM_000428
UniProt Q14767
Other data
Locus Chr. 14 q24.3
latent transforming growth factor beta binding protein 3
Identifiers
Symbol LTBP3
Alt. symbols LTBP2
Entrez 4054
HUGO 6716
OMIM 602090
RefSeq NM_021070
UniProt Q9NS15
Other data
Locus Chr. 11 q12
latent transforming growth factor beta binding protein 4
Identifiers
Symbol LTBP4
Alt. symbols LTBP-4, LTBP-4L
Entrez 8425
HUGO 6717
OMIM 604710
RefSeq NM_003573
UniProt Q8N2S1
Other data
Locus Chr. 19 q13.1-13.2

The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins.

LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of transforming growth factors. They interact with a variety of extracellular matrix proteins and may play a role in the regulation of TGF beta bioavailability.



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