The Experimental Medicine and Biology Institute (Spanish: Instituto de Biología y Medicina Experimental, IByME) is a research and development centre affiliated to the University of Buenos Aires, in Buenos Aires, Argentina.
The institute was privately founded on March 14, 1944 by Dr. Bernardo A. Houssay, Nobel Prize in Physiology and Medicine (1947) for his work in diabetes and the control of the carbohydrate metabolism. Drs. Eduardo Braun-Menéndez, Oscar Orías, Juan T. Lewis and Virgilio G. Foglia were co-founders. The founding of the Institute was motivated by the dismissal of Dr. Houssay, together with 150 other professors from the University of Buenos Aires, by the military government. Dr. Houssay became its director and brought to work with him several colleagues and students. The initiative was made possible by the support of Dr. Miguel F. Laphitzondo and others who granted financial contributions in memory of Juan B. Sauberán.
The institute was the first organization devoted to scientific research in Argentina. Its initial structure resembled that of the Rockefeller Institute for Medical Research (now Rockefeller University, New York, United States) and of the Pasteur Institute, Paris, France. In 1949, the Institute was established as a chartered foundation recognized by the National Bureau of Non-Profit Entitites (Registro Nacional de Entidades de Bien Público).