Henry Markram
| Henry Markram | |
|---|---|
Visualizing Synaptic Maps onto Neocortical Neurons
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| Born |
28 March 1962 South Africa |
| Nationality | Israel |
| Fields | Neurology |
| Institutions | École Polytechnique Fédérale de Lausanne |
| Alma mater |
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| Thesis | Acetylcholine interacts with the NMDA receptor through the phosphoinositide pathway (1991) |
| Doctoral advisor | Menahem Segal |
| Doctoral students |
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| Known for |
Blue Brain Project Human Brain Project Spike-timing-dependent plasticity |
| Notable awards | Fulbright Scholar |
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Website people |
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Henry Markram (born 28 March 1962 into Jewish family ) is a Professor at the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland and director of both the Blue Brain Project and the Human Brain Project.
Henry Markram obtained his Bachelor of Science degree (Hons) from Cape Town University, South Africa under the supervision of Rodney Douglas and his PhD from the Weizmann Institute of Science, Israel in 1991, under the supervision of Menahem Segal. During his PhD work, he discovered a link between acetylcholine and memory mechanisms by showing that acetylcholine modulates the primary receptor linked to synaptic plasticity.
Henry Markram met his future wife, Kamila Markram (born in 1975), at the Max Planck Institute for Brain Research in Frankfurt. They moved to the École polytechnique fédérale de Lausanne together and, in 2007, founded Frontiers Media.
Following his PhD, Markram went to the United States as a Fulbright Scholar at the National Institutes of Health (NIH), where he studied ion channels on synaptic vesicles. As a Minerva Fellow he then went to the Laboratory of Bert Sakmann at the Max Planck Institute, Heidelberg, Germany, where he discovered calcium transients in dendrites evoked by sub-threshold activity, and by single action potentials propagating back into dendrites. He also began studying the connectivity between neurons, describing in great detail how layer 5 pyramidal neurons are interconnected.
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