Max Planck Institute for Brain Research

The Max Planck Institute for Brain Research is located in Frankfurt, Germany. It was founded as Kaiser Wilhelm Institute for Brain Research in Berlin 1914, moved to Frankfurt-Niederrad in 1962 and more recently in a new building in Frankfurt-Riedberg. It is one of 83 institutes in the Max Planck Society (Max Planck Gesellschaft).

Research at the Max Planck Institute for Brain Research focuses on the operation of networks of neurons in the brain. The institute hosts three scientific departments (with directors Moritz Helmstaedter of the Helmstaedter Department, Gilles Laurent of the Laurent Department, and Erin Schuman of the Schuman Department), the Singer Emeritus Group, two Max Planck Research Groups, namely Johannes Letzkus' Neocortical Circuits Group and Tatjana Tchumatchenko's Theory of Neural Dynamics Group, as well as several additional research units. The common research goal of the Institute is a mechanistic understanding of neurons and synapses, of the structural and functional circuits which they form, of the computational rules which describe their operations, and ultimately, of their roles in driving perception and behavior. The experimental focus is on all scales required to achieve this understanding - from networks of molecules in dendritic compartments to networks of interacting brain areas. This includes interdisciplinary analyses at the molecular, cellular, multi-cellular, network and behavioral levels, often combined with theoretical approaches.

The "Kaiser-Wilhelm-Institut für Hirnforschung" (KWI for Brain Research) was founded in Berlin in 1914, making it one of the oldest institutes of the "Kaiser Wilhelm Society for the Advancement of Science", itself founded in 1911. It was based on the Neurologische Zentralstation (Neurological Center), a private research institute established by Oskar Vogt in 1898 and run together with his wife Cécile Vogt-Mugnier, also an accomplished brain researcher.

From 1901 to 1910, Vogt's coworker at this institute was Korbinian Brodmann, who in 1909 established the cytoarchitectonic classification of cortical areas still in use today (e.g., his area 17 is the primary visual cortex). Oskar Vogt's own scientific achievements also were in the field of cortical cytoarchitectonics and myeloarchitectonics.

In the 1920s Oskar Vogt became interested in the potential morphological correlates of mental abilities, and hence in the neuroanatomical study of 'elite brains'. When Lenin died of a brain hemorrhage in 1924, his brain was preserved in formaldehyde, where it remained for two years. In 1926, Vogt was recruited by the Soviet government to help establish Lenin's genius via histological investigation of his brain. He was given some space in Moscow to carry out this work and two years later, a spacious and representative brick building that had been confiscated from an American business. In it, he helped establish and then headed the Moscow Brain Institute. Between 1926 and 1930, Vogt travelled to Moscow several times to supervise the work on Lenin's brain by the Russian collaborators who had been trained at Vogt's KWI for Brain Research in Berlin.

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