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Haplogroup L2 (mtDNA)

Haplogroup L2
Possible time of origin 80,000-111,100 YBP
Possible place of origin West Africa or East Africa
Ancestor L2─6
Descendants L2a─d, L2e
Defining mutations 146, 150, 152, 2416, 8206, 9221, 10115, 13590, 16311!, 16390

Haplogroup L2 is a (mtDNA) haplogroup with a widespread modern distribution, particularly in Subequatorial Africa. Its L2a subclade is a somewhat frequent and widely distributed mtDNA cluster on the continent, as well as among African Americans.

L2 is a common lineage in Africa. It is believed to have evolved between 87,000 and 107,000 years ago or approx. 90,000 YBP. Its age and widespread distribution and diversity across the continent makes its exact origin point within Africa difficult to trace with any confidence. Several L2 haplotypes observed in Guineans and other West Africa populations shared genetic matches with East Africa and North Africa. An origin for L2b, L2c, L2d and L2e in West or Central Africa seems likely. The early diversity of L2 can be observed all over the African Continent, but as we can see in Subclades section below, the highest diversity is found in West Africa. Most of subclades are largely confined to West and western-Central Africa.

According to a 2015 study, "results show that lineages in Southern Africa cluster with Western/Central African lineages at a recent time scale, whereas, eastern lineages seem to be substantially more ancient. Three moments of expansion from a Central African source are associated to L2: one migration at 70–50 ka into Eastern or Southern Africa, postglacial movements 15–10 ka into Eastern Africa; and the southward Bantu Expansion in the last 5 ka. The complementary population and L0a phylogeography analyses indicate no strong evidence of mtDNA gene flow between eastern and southern populations during the later movement, suggesting low admixture between Eastern African populations and the Bantu migrants. This implies that, at least in the early stages, the Bantu expansion was mainly a demic diffusion with little incorporation of local populations".

L2 is the most common haplogroup in Africa, and it has been observed throughout the continent. It is found in approximately one third of Africans and their recent descendants.

The highest frequency occurs among the Mbuti Pygmies (64%). Important presence in Western Africa, specially in Senegal (43-54%). Also important in Non-Bantu populations of East Africa (44%), in Sudan and Mozambique.


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