Haplogroup D (Y-DNA)

Haplogroup D-M174
Possible time of origin	50,000 - 60,000 years BP
Possible place of origin	Southeast-Asia
Ancestor	DE
Descendants	D-M15, , D-P99
Defining mutations	M174, IMS-JST021355, PAGES00003

In human genetics, Haplogroup D-M174 is a Y-chromosome haplogroup. Both D-M174 and E lineages also exhibit the single-nucleotide polymorphism M168 which is present in all Y-chromosome haplogroups except A and B, as well as the YAP unique-event polymorphism, which is unique to Haplogroup DE.

Haplogroup D-M174 is believed to have originated in Asia some 60,000 years before present. While haplogroup D-M174 along with haplogroup E contains the distinctive YAP polymorphism (which indicates their common ancestry), no haplogroup D-M174 chromosomes have been found anywhere outside of Asia.

It is found today at high frequency among populations in Tibet, the Japanese archipelago, and the Andaman Islands, though curiously not in India. The Ainu of Japan are notable for possessing almost exclusively Haplogroup D-M174 chromosomes, although Haplogroup C-M217 chromosomes also have been found in 15% (3/20) of sampled Ainu males. Haplogroup D-M174 chromosomes are also found at low to moderate frequencies among populations of Central Asia and northern East Asia as well as the Han and Miao–Yao peoples of China and among several minority populations of Sichuan and Yunnan that speak Tibeto-Burman languages and reside in close proximity to the Tibetans.

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