Haplogroup C-F3393

Haplogroup C1 F3393
Possible time of origin	about 48,400 years
Possible place of origin	probably South Asia
Ancestor	Haplogroup C
Descendants	C1a CTS11043; C1a1 M8; C1a2 V20 (previously C6); C1a2 (previously C6) V20; C1b1a B66/Z16458; C1b1a1 M356; (previously C5); C1b2a M38 (previously C2); C1b2a1a P33; C1b2b (previously C4) M347
Defining mutations	F3393

Haplogroup C1 also known as C-F3393, is a major Y-chromosome haplogroup. It is one of two primary branches of the broader Haplogroup C, the other being C2 (also known as C-M217; the former Haplogroup C3).

The basal paragroup, C1* (C-F3393*), has not been found, in samples from living or dead males. Of the two primary branches, C1b is common in parts of Oceania and Asia, whereas C1a is extremely rare worldwide and has been found only amongst individuals native to Japan, Nepal, and Southern Europe.

The paragroup C1* (C-F3393*) and its subclades are the predominant Y-DNA haplogroups among peoples indigenous to Australia, some of the Pacific Islands and South Asia. Other subclades are found, at very low frequencies, in isolated locations throughout the Eurasian landmass and adjoining islands.

It is likely that more than 40% of indigenous Australian males belonged to the subclade C1b2b (C-M347) known previously as C4, before contact with European settlers. Within C-M347 at least two subclades have been identified: C1b2b1 (DYS390.1del,M210) and an as yet unresolved offshoot of the C1b2b1 paragroup (i.e. M347xDYS390.1del,M210).

C1b2a (M38), previously known as C2, is virtually restricted to Island South East Asia, New Guinea, Melanesia, and Polynesia. Of its subclades, C1b2a1a (P33) is found at a high frequency among Polynesians.

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