JSC "Domodedovo Airlines" (Russian: ОАО «Авиакомпания «Домодедовские авиалинии» OAO Aviakompaniya Domodedovskiye Avialinii) was an airline with its head office on the grounds of Domodedovo International Airport in Domodedovsky District, Moscow Oblast, Russia. It operated scheduled flights within Russia and the CIS, with a focus on flights to the Russian Far East. The airline also operated scheduled and ad hoc charter flights to P. R. China, Europe, Thailand, Maldives, Malaysia and Singapore. It was based at Moscow's Sheremetyevo International Airport.

Domodedovo United Air Detachment (Russian: Домодедовского объединенного авиаотряда Domodedovskogo Obyedinennogo Aviaotryada), a division of Aeroflot Soviet Airlines, was established in March 1964, when Flight Units 206, 211 and 202 were transferred to Sheremetyevo Airport from Vnukovo Airport. The division was set up to operate long-haul services within the USSR, particularly to the Russian Far East and the Central Asian republics. All flights of the airline were operated as part of Aeroflot services.

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