Dibutyl phthalate
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| Names | |
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Preferred IUPAC name
Dibutyl benzene-1,2-dicarboxylate
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| Other names
Dibutyl phthalate
Di-n-butyl phthalate Butyl phthalate n-Butyl phthalate 1,2-Benzenedicarboxylic acid dibutyl ester o-Benzenedicarboxylic acid dibutyl ester DBP Palatinol C Elaol Dibutyl 1,2-benzene-dicarboxylate |
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| Identifiers | |
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3D model (Jmol)
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.001.416 |
| EC Number | 201-557-4 |
| KEGG | |
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PubChem CID
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| RTECS number | TI0875000 |
| UNII | |
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| Properties | |
| C16H22O4 | |
| Molar mass | 278.35 g·mol−1 |
| Appearance | Colorless to faint yellow oily liquid |
| Odor | aromatic |
| Density | 1.05 g/cm3 at 20 °C |
| Melting point | −35 °C (−31 °F; 238 K) |
| Boiling point | 340 °C (644 °F; 613 K) |
| 13 mg/L (25 °C) | |
| log P | 4.72 |
| Vapor pressure | 0.00007 mmHg (20°C) |
| -175.1·10−6 cm3/mol | |
| Pharmacology | |
| P03BX03 (WHO) | |
| Hazards | |
| Main hazards | N), Harmful (Xi) |
| R-phrases | R50 R61 R62 |
| S-phrases | S45 S53 S61 |
| NFPA 704 | |
| Flash point | 157 °C (315 °F; 430 K) (closed cup) |
| 402 °C (756 °F; 675 K) | |
| Explosive limits | 0.5 - 3.5% |
| Lethal dose or concentration (LD, LC): | |
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LD50 (median dose)
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5289 mg/kg (oral, mouse) 8000 mg/kg (oral, rat) 10,000 mg/kg (oral, guinea pig) |
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LC50 (median concentration)
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4250 mg/m3 (rat) 25000 mg/m3 (mouse, 2 hr) |
| US health exposure limits (NIOSH): | |
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PEL (Permissible)
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TWA 5 mg/m3 |
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REL (Recommended)
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TWA 5 mg/m3 |
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IDLH (Immediate danger)
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4000 mg/m3 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 (what is   ?) |
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| Infobox references | |
Dibutyl phthalate (DBP) is a commonly used plasticizer. It is also used as an additive to adhesives or printing inks. It is soluble in various organic solvents, e.g. in alcohol, ether and benzene. DBP is also used as an ectoparasiticide. DBP is also a putative endocrine disruptor
The use of this substance in cosmetics, including nail polishes, is banned in the European Union under Directive 76/768/EEC 1976.
The use of DBP has been restricted in the European Union for use in children's toys since 1999.
An EU Risk Assessment has been conducted on DBP and the final outcome has now been published in the EU Official Journal. To eliminate a potential risk to plants in the vicinity of processing sites and workers through inhalation, measures are to be taken within the framework of the IPPC Directive (96/61/EC) and the Occupational Exposure Directive (98/24/EC) Also includes the 2004 addendum.
DBP was added to the California Proposition 65 (1986) list of suspected teratogens in November 2006. It is a suspected endocrine disruptor. It was used in some nail polishes; all major producers began eliminating this chemical from nail polishes in the Fall of 2006.
DBP was permanently banned in children's toys, in concentrations of 1000 ppm or greater, under section 108 of the Consumer Product Safety Improvement Act of 2008 (CPSIA).
DBP is produced by the reaction of n-butanol with phthalic anhydride. It is or was produced in the United States by Eastman Chemical Company, but the company announced in March 2011 that it would end production and exit the DBP and DEP (diethyl phthalate) market in December 2011.
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