DEPDC1B

DEPDC1B
Identifiers
Aliases	DEPDC1B, BRCC3, XTP1, DEP domain containing 1B
External IDs	MGI: 2145425 HomoloGene: 10157 GeneCards: DEPDC1B
Gene location (Human) Chr. Chromosome 5 (human) Band 5q12.1 Start 60,596,912 bp End 60,700,190 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 D2.1 Start 108,316,332 bp End 108,407,782 bp
Gene ontology Molecular function • GTPase activator activity Cellular component • cytosol Biological process • positive regulation of Wnt signaling pathway • positive regulation of GTPase activity • intracellular signal transduction • regulation of small GTPase mediated signal transduction • cell migration • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55789	218581
Ensembl	ENSG00000035499	ENSMUSG00000021697
UniProt	Q8WUY9	Q8BH88
RefSeq (mRNA)	NM_001145208 NM_018369	NM_178683
RefSeq (protein)	NP_001138680 NP_060839	NP_848798
Location (UCSC)	Chr 5: 60.6 – 60.7 Mb	Chr 5: 108.32 – 108.41 Mb
PubMed search

55789

218581

ENSG00000035499

ENSMUSG00000021697

Q8WUY9

Q8BH88

NM_001145208
NM_018369

NM_178683

NP_001138680
NP_060839

NP_848798

DEP Domain Containing Protein 1B also known as XTP1, XTP8,HBV XAg-Transactivated Protein 8, [formerly referred to as BRCC3] is a human protein encoded by a gene of similar name located on chromosome 5.

The precise function of DEPDC1B is currently unknown. Expression profiles indicate that DEPDC1B is highly expressed ubiquitously throughout human tissue.

DEPDC1B is found on the long arm of chromosome 5 (5q12.1), spanning 103kb on the minus strand. The gene neighborhood of DEPDC1B includes 5 other genes. Downstream are two genes SEPT21 and PDE4D. Upstream are another two genes ELOV7 and KRT8P31. On the complement strand is another gene in the same region PART1.

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Wikipedia