Cubana de Aviación S.A., commonly known as Cubana, is a national airline based in Cuba, as well as the country's largest airline. It was founded in October 1929 (1929-10), becoming one of the earliest airlines to emerge in Latin America. It has its corporate headquarters in Havana, and its main base is located at José Martí International Airport. Originally a subsidiary of Pan American World Airways and later a private company owned by Cuban investors, Cubana has been wholly owned by the Cuban government since May 1959 and celebrated its 80th anniversary in 2009.

Cubana was a founder and is a current member of the International Air Transport Association, the International Association of Aeronautical Telecommunications (SITA) and the International Association of Latin American Air Transportation (AITAL).

The airline was established on 8 October 1929 as Compañía Nacional Cubana de Aviación Curtiss S.A., initially as a flying school as well as a charter carrier, beginning scheduled services in 1930. The airline's name indicated its association with the Curtiss aircraft manufacturing company. Cubana's early fleet used Curtiss Robin, amphibian Sikorsky S-38, Ford Trimotor, and Lockheed Electra (L-10) aircraft. Pan American acquired Cubana in 1932, and the word Curtiss was deleted from the carrier's name. By the end of the decade, the carrier had a fleet of four Ford Trimotors and three Lockheed Electras that operated on the domestic Havana–Camaguey, Havana–Guantanamo–Baracoa and Santiago–Baracoa routes.

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