CXCL2

chemokine (C-X-C motif) ligand 2
Identifiers
Symbol	CXCL2
Alt. symbols	SCYB2, GRO2, GROb, MIP-2a, MGSA-b, CINC-2a
Entrez	2920
HUGO	4603
OMIM	139110
RefSeq	NM_002089
UniProt	P19875
Other data
Locus	Chr. 4 q21

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

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