CALCRL

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3AQF, 3N7P, 3N7R, 3N7S, 4RWF

Identifiers

CALCRL, CGRPR, CRLR, calcitonin receptor like receptor

External IDs

Gene ontology
Molecular function	• adrenomedullin receptor activity • G-protein coupled receptor activity • calcitonin receptor activity • signal transducer activity • protein transporter activity • protein binding • calcitonin gene-related peptide receptor activity • transmembrane signaling receptor activity
Cellular component	• integral component of membrane • endosome • membrane • plasma membrane • integral component of plasma membrane • endoplasmic reticulum • lysosome
Biological process	• positive regulation of cAMP biosynthetic process • G-protein coupled receptor signaling pathway • negative regulation of smooth muscle contraction • adenylate cyclase-activating G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • receptor internalization • cellular response to sucrose stimulus • heart development • cell surface receptor signaling pathway • angiogenesis • positive regulation of cell proliferation • protein transport • negative regulation of inflammatory response • calcium ion transport • signal transduction • positive regulation of smooth muscle cell proliferation • cAMP biosynthetic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


10203


54598


ENSG00000064989


ENSMUSG00000059588


Q16602


Q9R1W5

RefSeq (mRNA)


NM_001271751 NM_005795


NM_018782

RefSeq (protein)


NP_001258680 NP_005786


NP_061252

Location (UCSC)

PubMed search

Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein.

The protein encoded by the CALCRL gene is a G protein-coupled receptor related to the calcitonin receptor. CALCRL is linked to one of three single transmembrane domain receptor activity-modifying proteins (RAMPs) that are essential for functional activity.