Calcitonin receptor

CALCR
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5II0
Identifiers
Aliases	CALCR, CRT, CT-R, CTR, CTR1, calcitonin receptor
External IDs	MGI: 101950 HomoloGene: 1320 GeneCards: CALCR
Gene ontology Molecular function • G-protein coupled receptor activity • calcitonin receptor activity • calcitonin binding • signal transducer activity • protein transporter activity • protein binding • transmembrane signaling receptor activity • receptor activity Cellular component • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • cell Biological process • positive regulation of cAMP biosynthetic process • positive regulation of adenylate cyclase activity • adenylate cyclase-activating G-protein coupled receptor signaling pathway • positive regulation of cytosolic calcium ion concentration • receptor internalization • response to glucocorticoid • activation of phospholipase C activity • activation of adenylate cyclase activity • cell surface receptor signaling pathway • protein transport • protein localization to plasma membrane • signal transduction • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	799	12311
Ensembl	ENSG00000004948	ENSMUSG00000023964
UniProt	P30988	Q60755
RefSeq (mRNA)	NM_001742 NM_001164737 NM_001164738	NM_001042725 NM_007588
RefSeq (protein)	NP_001158209 NP_001158210 NP_001733	NP_001036190.1 NP_031614.2 NP_001036190 NP_031614
Location (UCSC)	Chr 7: 93.42 – 93.57 Mb	Chr 6: 3.69 – 3.76 Mb
PubMed search

5II0

799

12311

ENSG00000004948

ENSMUSG00000023964

P30988

Q60755

NM_001742
NM_001164737
NM_001164738

NM_001042725
NM_007588

NP_001158209
NP_001158210
NP_001733

NP_001036190.1
NP_031614.2
NP_001036190
NP_031614

The calcitonin receptor (CT) is a G protein-coupled receptor that binds the peptide hormone calcitonin and is involved in maintenance of calcium homeostasis, particularly with respect to bone formation and metabolism.

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