Big Brother Africa 6 (also known as Big Brother Africa: Amplified) was the sixth season of the Big Brother Africa reality television series produced by Endemol for M-Net which began airing on 1 May 2011 and ran for 91 days until 31 July 2011. This year Mnet co-partnered with Coca-Cola for the series. Ikponmwosa "IK" Osakioduwa came back to host the show for the third time in a row. The launch show was also broadcast live through the official website. This year the contestants will move into a brand new house. South African band BLKJKS (Blackjacks) performed their song 'Mzabalazo'; Busta Rhymes also performed during the 2 hour launch show.
There were twenty six housemates this season and lived in the same house (Heads House) for one week. On Day 7, eleven of the twenty six moved to a different house (Tails House) during the live eviction show. The housemates were competing for US$400,000. On Day 42, it was announced that there were going to be two winners who will each receive US$200,000. This year, fourteen countries participated in the season. Each country had at least one representative for them. All fourteen countries were returning countries and these were Angola, Botswana, Ethiopia, Ghana, Kenya, Malawi, Mozambique, Namibia, Nigeria, South Africa, Tanzania, Uganda, Zambia and Zimbabwe.
On Day 1, twenty six housemates entered the House on launch night.
This season, a twist known as the Fuse took place since Day 35. The Fuse was a punishment that was given to housemate(s) for a week until the live eviction show. The fuses were given to them by the evicted housemates. The Fuse is similar to the "Molotov Cocktail" in season 4 and the "Dagger" in season 5.