Basilea Pharmaceutica

Basilea Pharmaceutica AG

Type	Public (SIX: BSLN)
Industry	Pharmaceuticals
Founded	2000
Headquarters	Basel, Switzerland
Key people	Ronald Scott, (CEO) Domenico Scala (Chairman of the board)
Products	Isavuconazole, Ceftobiprole, Alitretinoin
Number of employees	196
Website	basilea.com

Basilea Pharmaceutica is a multinational specialty biopharmaceutical company headquartered in Basel, Switzerland. It was formed as a spin-off entity from the drug giant Hoffmann–La Roche in October 2000. It is engaged in the development of antibiotics, antifungals and oncology drugs for treatment of invasive aspergillosis and invasive mucormycosis. Basilea is publicly traded on the SIX Swiss exchange (SIX:BSLIN).

The company is based in Basel, Switzerland. It has subsidiaries in France (Basilea Pharmaceuticals SAS), Germany (Basilea Pharmaceuticals GmbH), Denmark (Basilea Pharmaceuticals A/S), the People's Republic of China (Basilea Pharmaceutica China Ltd), Spain (Basilea Pharmaceuticals Iberia SL), the United Kingdom (Basilea Pharmaceuticals Ltd.), and the United States of America (Basilea Pharmaceuticals Inc.). According to stock filings, it had 196 employees as of June 2007.

Among the company’s notable products is Isavuconazole (CRESEMBA) an intravenous and oral antifungal, received orphan drug status designation by the United States Food and Drug Administration (FDA) in 2013. The company also manufactures pharmaceuticals for use against methicillin-resistant Staphylococcus aureus.

Basilea Pharmaceutica was founded in 2000 as a spin-off entity of pharmaceutical giant Hoffman-LaRoche. In 2002, the company founded Basilea Pharmaceutica China Ltd., a research facility located in Haimen Technology Development Zone, north of Shanghai, China, which it operates as a wholly owned subsidiary. Basilea is marketing Toctino (alitretinoin), for the treatment of severe chronic hand eczema, in Denmark, France, Germany, Switzerland and the United Kingdom. The drug is approved in 14 additional European countries as well as in Canada and has been recommended for approval in eight further European countries. Ceftobiprole is acephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus being developed in cooperation with Johnson & Johnson was approved in Europe in October 2013.Isavuconazole, a broad-spectrum triazole antifungal drug in Phase III clinical development has won orphan drug status in the United States. Basilea partnered with pharmaceutical company Astellas Pharma Inc., which holds the U.S. rights to the drug, to conduct two phase 3 clinical trials. The trials demonstrated safety and efficacy in adults with invasive fungal infections. Following these trials, the FDA granted approval for the use of isavuconazole in patients with invasive aspergillosis and invasive mucomycoses, diseases that typically occur in immunocompromised patients.