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Ascariasis

Ascariasis
Ascaris infection in X-ray image- Duedenal worms - in the first portion of the bowel after the stomach (South Africa) (16238958958).jpg
High number of ascaris worms – visible as black tangled mass – are filling the duodenum, the first portion of the bowel after the stomach, of this South African patient (X-ray image with barium as contrast medium)
Classification and external resources
Specialty Infectious disease
ICD-10 B77
ICD-9-CM 127.0
OMIM 604291
DiseasesDB 934
MedlinePlus 000628
eMedicine article/212510
MeSH D001196
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Ascariasis is a disease caused by the parasitic roundworm Ascaris lumbricoides. Infections have no symptoms in more than 85% of cases, especially if the number of worms is small. Symptoms increase with the number of worms present and may include shortness of breath and fever in the beginning of the disease. These may be followed by symptoms of abdominal swelling, abdominal pain, and diarrhea. Children are most commonly affected, and in this age group the infection may also cause poor weight gain, malnutrition, and learning problems.

Infection occurs by eating food or drink contaminated with Ascaris eggs from feces. The eggs hatch in the intestines, burrow through the gut wall, and migrate to the lungs via the blood. There they break into the alveoli and pass up the trachea, where they are coughed up and swallowed. The larvae then pass through the stomach for a second time into the intestine, where they become adult worms. Ascariasis is classified as a neglected tropical disease as it is a type of soil-transmitted helminthiasis. These diseases are in turn part of a group of diseases called helminthiases.

Prevention is by improved sanitation, which includes improving access to toilets and proper disposal of feces.Handwashing with soap appears protective. In areas where more than 20% of the population is affected, treating everyone at regular intervals is recommended. Reoccurring infections are common. There is no vaccine. Treatments recommended by the World Health Organization are the medications albendazole, mebendazole, levamisole, or pyrantel pamoate. Other effective agents include tribendimidine and nitazoxanide.


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