Tribendimidine

Tribendimidine

Clinical data
ATC code	none
Identifiers
IUPAC name N,N'-bis(4-(1-dimethylamino)ethylideneaminophenyl)-1,4 -phenylene dimethylidyneamine
CAS Number	115103-15-6 N
PubChem CID	3086564
ChemSpider	2343161 Y
ChEMBL	CHEMBL427256 N
Chemical and physical data
Formula	C28H32N6
Molar mass	452.594 g/mol
3D model (JSmol)	Interactive image
SMILES N(=C/c2ccc(\C=N\c1ccc(/N=C(/N(C)C)C)cc1)cc2)\c3ccc(\N=C(\N(C)C)C)cc3
InChI InChI=1S/C28H32N6/c1-21(33(3)4)31-27-15-11-25(12-16-27)29-19-23-7-9-24(10-8-23)20-30-26-13-17-28(18-14-26)32-22(2)34(5)6/h7-20H,1-6H3/b29-19+,30-20+,31-21+,32-22+ Y Key:XOIOGKHKNQYULW-HTNNXBMUSA-N Y
NY (what is this?)

Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai. It is a derivative of amidantel.

In clinical trials, it was highly effective in treating ankylostomiasis, ascariasis and enterobiasis. However, animal studies suggest it is ineffective in treating Schistosoma mansoni or Fasciola hepatica disease. The drug has also performed well in trials against opisthorchiasis, curing about 70% of cases.

Tribendimidine is associated with Shandong Xinhua Pharmaceutical Company Limited in Zibo, Shandong, China.