Ammonium acetate

Ammonium acetate

Names
IUPAC name Ammonium ethanoate
Identifiers
CAS Number	631-61-8 Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:62947 N
ChemSpider	11925 Y
ECHA InfoCard	100.010.149
PubChem	517165
RTECS number	AF3675000
UNII	RRE756S6Q2 Y
InChI InChI=1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3 Y Key: USFZMSVCRYTOJT-UHFFFAOYSA-N Y InChI=1/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3 Key: USFZMSVCRYTOJT-UHFFFAOYAY
SMILES O=C(O)C.N
Properties
Chemical formula	C2H7NO2
Molar mass	77.08 g·mol−1
Appearance	White solid crystals, deliquescent
Odor	Slightly acetic
Density	1.17 g/cm3 (20 °C) 1.073 g/cm3 (25 °C)
Melting point	113 °C (235 °F; 386 K)
Solubility in water	102 g/100 mL (0 °C) 148 g/100 mL (4 °C) 143 g/100 mL (20 °C) 533 g/100 mL (80 °C)
Solubility	Soluble in alcohol, SO2, acetone, liquid ammonia
Solubility in methanol	7.89 g/100 mL (15 °C) 131.24 g/100 g (94.2 °C)
Solubility in dimethylformamide	0.1 g/100 g
Magnetic susceptibility (χ)	-41.1·10−6 cm3/mol
Structure
Crystal structure	Orthorhombic
Thermochemistry
Std enthalpy of formation (ΔfHo298)	−615 kJ/mol
Hazards
Main hazards	Irritant
Safety data sheet	JT Baker
GHS pictograms
GHS signal word	Warning
GHS hazard statements	H303, H316, H320, H333
GHS precautionary statements	P281, P335
NFPA 704	1 1 1
Flash point	136 °C (277 °F; 409 K)
Lethal dose or concentration (LD, LC):
LD50 (median dose)	386 mg/kg (mice, intravenous)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Ammonium acetate is a chemical compound with the formula NH₄CH₃CO₂. It is a white, hygroscopic solid and can be derived from the reaction of ammonia and acetic acid. It is available commercially.

It is the main precursor to acetamide:

It is also used as a diuretic.

As the salt of a weak acid and a weak base, ammonium acetate is often used with acetic acid to create a buffer solution. Ammonium acetate is volatile at low pressures. Because of this, it has been used to replace cell buffers with non-volatile salts in preparing samples for mass spectrometry. It is also popular as a buffer for mobile phases for HPLC with ELSD detection for this reason. Other volatile salts that have been used for this include ammonium formate.

Ammonium acetate is also used as a food additive as an acidity regulator; INS number 264. It is approved for usage in Australia and New Zealand.

Ammonium acetate is produced by the neutralization of acetic acid with ammonium carbonate or by saturating glacial acetic acid with ammonia. Obtaining crystalline ammonium acetate is difficult on account of its aqueous solution giving off ammonia when evaporated.