Alexander, Prince of Orange (Willem Alexander Karel Hendrik Frederik; 25 August 1851 – 21 June 1884), was heir apparent to his father King William III of the Netherlands from 11 June 1879 until his death.

For a span of 116 years, from the birth of Alexander (1851) until the birth of the present king Willem-Alexander (1967), no male heirs were born into the Dutch Royal House.

Prince Alexander of the Netherlands was born in The Hague on 25 August 1851. He was the third child of King William III and Queen Sophie. Unlike his brother William, the crown prince, he was disciplined, intellectual and well-read. After Prince William's death on 11 June 1879, he became heir apparent to the Dutch throne and as such the Prince of Orange.

Alexander held the position of heir apparent until his own death, at age 32, on 21 June 1884 in The Hague from typhus. Although he never married, negotiations were held for him to marry, firstly Princess Thyra of Denmark, and supposedly secondly the Infanta Marie Anne of Portugal. He was buried in the new royal burial vault in the Nieuwe Kerk in Delft on 17 July 1884. After his death, his half-sister, the future Queen Wilhelmina, became heiress presumptive to the Dutch throne. Alexander's death meant that on the death of William III the Grand Duchy of Luxembourg came into the hands of Duke Adolphus from the Walram line of the House of Nassau, as under the terms of the house-treaty a princess could not succeed to that title.

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