ASPN

ASPN
Identifiers
Aliases	ASPN, OS3, PLAP-1, PLAP1, SLRR1C, asporin
External IDs	MGI: 1913945 HomoloGene: 32357 GeneCards: ASPN
Gene location (Human) Chr. Chromosome 9 (human) Band 9q22.31 Start 92,456,205 bp End 92,482,506 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 A5 Start 49,544,443 bp End 49,567,565 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • calcium ion binding • protein kinase inhibitor activity • collagen binding Cellular component • cytoplasm • extracellular matrix • proteinaceous extracellular matrix • extracellular region Biological process • bone mineralization • biomineral tissue development • negative regulation of transforming growth factor beta receptor signaling pathway • negative regulation of tooth mineralization • negative regulation of protein kinase activity • cytokine-mediated signaling pathway • negative regulation of JAK-STAT cascade Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54829	66695
Ensembl	ENSG00000106819	ENSMUSG00000021388
UniProt	Q9BXN1	Q99MQ4
RefSeq (mRNA)	NM_017680 NM_001193335	NM_001172481 NM_025711
RefSeq (protein)	NP_001180264 NP_060150	NP_001165952 NP_079987
Location (UCSC)	Chr 9: 92.46 – 92.48 Mb	Chr 9: 49.54 – 49.57 Mb
PubMed search

54829

66695

ENSG00000106819

ENSMUSG00000021388

Q9BXN1

Q99MQ4

NM_017680
NM_001193335

NM_001172481
NM_025711

NP_001180264
NP_060150

NP_001165952
NP_079987

Asporin is a protein that in humans is encoded by the ASPN gene.

ASPN belongs to a family of leucine-rich repeat (LRR) proteins associated with the cartilage matrix. The name asporin reflects the unique aspartate-rich N terminus and the overall similarity to decorin (MIM 125255) (Lorenzo et al., 2001).

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Wikipedia