APOA4

APOA4
Identifiers
Aliases	APOA4, apolipoprotein A4
External IDs	OMIM: 107690 MGI: 88051 HomoloGene: 47927 GeneCards: APOA4
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	337	11808
Ensembl	ENSG00000110244	ENSMUSG00000032080
UniProt	n/a	P06728
RefSeq (mRNA)	NM_000482	NM_007468
RefSeq (protein)	n/a	NP_031494.2 NP_031494
Location (UCSC)	Chr 11: 116.82 – 116.82 Mb	Chr 9: 46.24 – 46.24 Mb
PubMed search

337

11808

ENSG00000110244

ENSMUSG00000032080

n/a

P06728

NM_000482

NM_007468

n/a

NP_031494.2
NP_031494

Apolipoprotein A-IV (also known as apoA-IV, apoAIV, or apoA4) is plasma protein that is the product of the human gene APOA4.

APOA4 resides on chromosome 11 in close linkage to APOA1 and APOC3. APOA4 contains 3 exons separated by two introns, and is polymorphic, although most of the reported sequence polymorphisms occur in exon 3. The best validated and studied non-synonymous SNPs are a glutamine → histidine substitution at codon 360 and a threonine → serine substitution at codon 347; a sequence polymorphism has also been identified in the 3'UTR of the third exon. Intra-species comparative gene sequence analysis suggests that the APOA4 gene arose from APOA1 by gene duplication approximately 270 MYA.

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Wikipedia