Chromosome 11

Chromosome 11 (human)
Pair of human chromosome 11 (after G-banding). One is from mother, one is from father.
Chromosome 11 pair in human male karyogram.
Features
Length (bp)	135,086,622 bp
Number of genes	2,920 2,893
Type	Autosome
Centromere position	Submetacentric
Identifiers
RefSeq	NC_000011
GenBank	CM000673

Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. In January 2017, two estimates differed insignificantly (0.3%), with one estimate giving 2,920 genes, and the other estimate giving 2,893 genes.

At 21.5 genes per megabase, Chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome.

More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene, and multi-gene, clusters along this chromosome.

The following are some of the genes located on chromosome 11:

The following diseases and disorders are some of those related to genes on chromosome 11: