6-IT

6-(2-Aminopropyl)indole

Clinical data
Routes of administration	Oral
Legal status
Legal status	Uncontrolled (but covered under the Federal Analogue Act in the United States and Australia and likely under similar bills in other countries)
Identifiers
IUPAC name 1-(1H-Indol-6-yl)propan-2-amine
CAS Number	22196-72-1
PubChem CID	30999
ChemSpider	28759
Chemical and physical data
Formula	C11H14N2
Molar mass	174.24 g/mol
3D model (Jmol)	Interactive image
SMILES C1=C2C(=CC=C1CC(C)N([H])[H])C=C[N]2[H]
InChI InChI=1S/C11H14N2/c1-8(12)6-9-2-3-10-4-5-13-11(10)7-9/h2-5,7-8,13H,6,12H2,1H3 Y Key:QCFIFKAOUKPFPU-UHFFFAOYSA-N Y

6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative with no history of use in humans. The analogue 5-API is known to be psychoactive, indicating 6-API may also be psychoactive by the same structure-activity relationship that links 5-APB and 6-APB.

Alexander Shulgin says in his book TiHKAL "From the normal 3-position to the 2, the 4, the 5, the 6 or the 7-positions. All five alpha-methyltryptamine isomers are known, but only one is known to be active in man as a CNS active material. This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT"[1].

Studies in dogs have also shown the drug to increase hemoglobin levels in the bloodstream.