Men's Singles | |
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2016 Internazionali BNL d'Italia | |
Champion | Andy Murray |
Runner-up | Novak Djokovic |
Final score | 6–3, 6–3 |
Novak Djokovic was the two-time defending champion, but lost to Andy Murray in the final, 3–6, 3–6. This was the first edition since 2004 not won by either Rafael Nadal or Novak Djokovic.
The top eight seeds receive a bye into the second round.