The 2012 Copa Claro was a men's tennis tournament played on outdoor clay courts. It was the 15th edition of the Copa Claro, and it was part of the ATP World Tour 250 series of the 2012 ATP World Tour. It took place in Buenos Aires, Argentina, from February 18 through February 26, 2012. David Ferrer won the singles title.

The following players received wildcards into the main draw:

The following players received entry from the qualifying draw:

The following player received entry as Lucky Loser:

The following pairs received wildcards into the doubles main draw:

The following pair received entry as alternates:

David Ferrer defeated Nicolás Almagro 4–6, 6–3, 6–2

David Marrero / Fernando Verdasco defeated Michal Mertiňák / André Sá 6–4, 6–4