The knockout stage of the 2007–08 UEFA Champions League began on 19 February 2008, and concluded on 21 May 2008 with the final at the Luzhniki Stadium, Moscow. The knockout stage involves the 16 teams who finished in the top two in each of their groups in the group stage.
Each tie in the knockout stage, apart from the final, will be played over two legs, with each team playing one leg at home. The team that has the higher aggregate score over the two legs will progress to the next round. In the event that aggregate scores finish level, the team that scored more goals away from home over the two legs will progress. If away goals are also equal, 30 minutes of extra time are played. If there are goals scored during extra time and the aggregate score is still level, the visiting team qualifies by virtue of more away goals scored. If no goals are scored during extra time, there will be a penalty shootout after extra time.
In the final, the tie is played over just one leg at a neutral venue. If scores are level at the end of normal time in the final, extra time is played, followed by penalties if scores remain tied.
The draw for the first knockout round of the 2007–08 UEFA Champions League was held on 21 December 2007 at 12:00 CET in Nyon, Switzerland. The first legs of the first knockout round were played on 19 February and 20 February 2008, while the second legs were played on 4 March, 5 March and, in the case of Internazionale and Liverpool, 11 March, due to a stadium clash with the match between Milan and Arsenal.
All times CET