The 2007–08 UEFA Champions League group stage matches took place between 18 September and 12 December 2007.
Seeding was determined by the UEFA coefficients. Clubs from the same association were paired up to split the matchdays between Tuesday and Wednesday. Clubs with the same pairing letter would play on different days, ensuring that teams from the same city (e.g. Milan and Internazionale, who also share a stadium) did not play on the same day.
* Due to the death of Antonio Puerta, the second leg of Sevilla's game against AEK Athens was postponed until 3 September, while the draw was held on 30 August. Due to the seeding criteria, both clubs were included in the draw interchangeably and their seeding was determined by the higher of the two teams' coefficients (Sevilla: 87.374, AEK Athens: 36.415). Sevilla was paired with Valencia (E), while AEK Athens was paired with Olympiacos (M). Eventually, Sevilla qualified for the group stage with a 6–1 win on aggregate against AEK Athens.
Based on paragraph 6.05 in the UEFA regulations for the current season, if two or more teams are equal on points on completion of the group matches, the following criteria are applied to determine the rankings:
All times CET