2006 US Open – Girls' Singles
| Girls' Singles | |
|---|---|
| 2006 US Open | |
| Champion |
 Anastasia Pavlyuchenkova
|
| Runner-up |
 Tamira Paszek
|
| Final score | 3–6, 6–4, 7–5 |
The girls' singles tournament of the 2006 US Open was won by Anastasia Pavlyuchenkova, who beat Tamira Paszek in the final by 3–6, 6–4, 7–5.
Victoria Azarenka was the defending champion, but she did not participate in the juniors' this year, having already been elevated to the seniors'.
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