2005–06 FIBA EuroCup Challenge
| 2005–06 FIBA EuroCup Challenge | |
|---|---|
| League | FIBA EuroCup Challenge |
| Sport | Basketball |
| Finals | |
| Champions |
 Ural Great Perm
|
| Runners-up |  Khimik |
The 2005–06 FIBA EuroCup Challenge was the 4th edition of Europe's fourth-tier level transnational competition for men's professional basketball clubs. This season, 24 teams participated. Russian team Ural Great Perm won the title, by beating Khimik in the dounle final.
The top 16 were two-legged ties determined on aggregate score. The first legs was played on December 8. All return legs were played on December 15.
The quarterfinals were two-legged ties determined on aggregate score. The first legs was played on January 19. All return legs were played on January 26.
The semifinals were two-legged ties determined on aggregate score. The first legs was played on February 23. All return legs were played on March 2.
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