The 1988 Enzed Sandown 500 was an endurance race for Group 3A Touring Cars. The event was held at the Sandown International Raceway in Victoria, Australia on 11 September 1988 over 129 laps of the 3.9 km circuit, a total distance of 503 km. This was the last time that the 3.9 km International configuration of the Sandown circuit was used for Australian touring car racing. The race was the 23rd running of the "Sandown enduro".
1988 would be the only year that New Zealand based hydraulic hose and connector repair company Enzed, a former sponsor of Larry Perkins, would sponsor the event.
Allan Moffat and Gregg Hansford won the race in their Eggenberger built Ford Sierra RS500. It was Moffat's 6th and final Sandown enduro win having previously won in 1969, 1970, 1974, 1982 and 1983. It was also Moffat's final race win as a driver in Australia. Second was the new Holden VL Commodore SS Group A SV of Larry Perkins and Denny Hulme, while third after numerous troubles was the pole winning Sierra of Dick Johnson and John Bowe.
Class B was won by the Mobil 1 Racing BMW M3 of Peter Brock, Jim Richards and David Parsons which finished 7th outright, 7 laps down on the Moffat/Hansford Sierra. Class C was won by the Nissan Gazelle of David Sala and Ross Burbidge which finished 11th outright, 20 laps down on the Sierra.