The 1980 US Open was a tennis tournament played on outdoor hard courts at the USTA National Tennis Center in New York City in New York in the United States. It was the 100th edition of the US Open and was held from August 26 to September 7, 1980.

John McEnroe defeated Björn Borg 7–6 ^(7–4), 6–1, 6–7^(5–7), 5–7, 6–4

Chris Evert-Lloyd defeated Hana Mandlíková 5–7, 6–1, 6–1