ZNF10

ZNF10
Identifiers
Aliases	ZNF10, KOX1, zinc finger protein 10
External IDs	HomoloGene: 130674 GeneCards: ZNF10
Gene location (Human) Chr. Chromosome 12 (human) Band 12q24.33 Start 133,130,575 bp End 133,159,465 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • protein binding • metal ion binding • nucleic acid binding Cellular component • intracellular • nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7556	n/a
Ensembl	ENSG00000256223	n/a
UniProt	P21506	n/a
RefSeq (mRNA)	NM_015394	n/a
RefSeq (protein)	NP_056209	n/a
Location (UCSC)	Chr 12: 133.13 – 133.16 Mb	n/a
PubMed search		n/a

7556

n/a

ENSG00000256223

n/a

P21506

n/a

NM_015394

n/a

NP_056209

n/a

Zinc finger protein 10 is a protein that in humans is encoded by the ZNF10 gene.

The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein.

ZNF10 has been shown to interact with TRIM28.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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