Xiaoliang Sunney Xie
| Xiaoliang Sunney Xie | |
|---|---|
 |
|
| Born |
June 24, 1962 Beijing, China |
| Fields |
Biophysical Chemistry, Optical Imaging, Genomics |
| Institutions |
Harvard University Peking University |
| Education | BSc in Chemistry from Peking University PhD in Physical Chemistry from UC San Diego |
| Known for | Single Molecule Enzymology, Coherent Raman Imaging, Single Cell Genomics |
| Notable awards |
Albany Prize in Medicine and Biomedical Research 2015, Peter Debye Award in Physical Chemistry 2015, Ellis R. Lippincott Award 2013, Biophysical Society Founders Award 2012 |
Xiaoliang Sunney Xie (Chinese: 谢晓亮; born 1962 in Beijing, China) is the Mallinckrodt Professor of Chemistry and Chemical Biology at Harvard University. Xie is considered a founding father of single-molecule enzymology.
Xie received a B.S. in chemistry from Peking University, followed by his Ph.D. in 1990 from the University of California at San Diego. He conducted postdoctoral research at the University of Chicago and in 1992 joined Pacific Northwest National Laboratory, where he later became a Chief Scientist. In 1999, he became the first full professor at Harvard University from the People's Republic of China since China's reform in 1978.
Xie has made major contributions to the emergence of the field of single-molecule biophysical chemistry and its application to biology. In particular, his group pioneered single-molecule enzymology and live cell studies of gene expression and regulation on a single molecule basis. He also led the development of coherent anti-Stokes Raman spectroscopy microscopy(CARS) and stimulated Raman scattering microscopy(SRS), enabling sensitive 3D imaging of live cells and organisms based on vibrational spectroscopy. In addition, his team developed methods for sequencing the genome of a single human cell with high precision, which has been applied to in vitro fertilization, allowing many new borns to avoid genetic disorders.
Single Cell Genomics
Coherent Raman Microscopy
Gene Expression and Regulation - Live Cell Single Molecule Studies
Single Molecule Enzymology
Single Molecule Spectroscopy and Imaging
...
Wikipedia