Wilson is a town in Niagara County, New York, United States. The population was 5,993 at the 2010 census. The town is said to be named after an early settler.

The Town of Wilson is on the northern border of the county and contains a village, also called Wilson.

The Town of Wilson was established in 1818. The origin of the town name is Reuben Wilson, one of the earliest pioneers of the town.

The Morse Cobblestone Farmhouse was listed on the National Register of Historic Places in 2010.

According to the United States Census Bureau, the town has a total area of 51.5 square miles (133.3 km²), of which, 49.5 square miles (128.3 km²) of it is land and 1.9 square miles (5.0 km²) of it (3.75%) is water.

The Town of Wilson is on the south shore of Lake Ontario.

North-south highway New York State Route 425 (Wilson-Cambria Road) intersects New York State Route 18 (Seaway Trail) in Wilson village.

As of the census of 2000, there were 5,840 people, 2,224 households, and 1,672 families residing in the town. The population density was 117.9 people per square mile (45.5/km²). There were 2,438 housing units at an average density of 49.2/sq mi (19.0/km²). The racial makeup of the town was 97.57% White, 0.38% Black or African American, 0.53% Native American, 0.26% Asian, 0.03% Pacific Islander, 0.36% from other races, and 0.87% from two or more races. Hispanic or Latino of any race were 0.84% of the population.

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