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Wilhelm Kuhne

Wilhelm Kühne
Wilhelm Kuhne.jpg
Born (1837-03-28)28 March 1837
Free City of Hamburg
Died 10 June 1900(1900-06-10) (aged 63)
Heidelberg, German Empire
Nationality German
Fields Physiology, Physiological chemistry
Institutions University of Berlin
University of Amsterdam
University of Heidelberg
Alma mater University of Göttingen
Doctoral advisor Rudolph Wagner
Other academic advisors Friedrich Wöhler
Doctoral students Russell Chittenden
Known for Coining the word "enzyme"
Discovery of trypsin

Wilhelm Friedrich Kühne (28 March 1837 – 10 June 1900) was a German physiologist. Born in Hamburg, he is best known today for coining the word enzyme.

Kühne was born at Hamburg on 28 March 1837. After attending the gymnasium in Lüneburg, he went to Göttingen, where his master in chemistry was Friedrich Wöhler and in physiology Rudolph Wagner. Having graduated in 1856, he studied under various famous physiologists, including Emil du Bois-Reymond at Berlin, Claude Bernard in Paris, and KFW Ludwig and EW von Brücke in Vienna.

At the end of 1863 he was put in charge of the chemical department of the pathological laboratory at Berlin, under Rudolf Virchow; in 1868 he was appointed professor of physiology at Amsterdam; and in 1871 he was chosen to succeed Hermann von Helmholtz in the same capacity at Heidelberg, where he died on 10 June 1900.

Kühne's original work falls into two main groups, the physiology of muscle and nerve, which occupied the earlier years of his life, and the chemistry of digestion, which he began to investigate while at Berlin with Virchow. In 1876, he discovered the protein-digesting enzyme trypsin.


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