urea carboxylase | |||||||||
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Identifiers | |||||||||
EC number | 6.3.4.6 | ||||||||
CAS number | 9058-98-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Search | |
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PMC | articles |
PubMed | articles |
NCBI | proteins |
In enzymology, an urea carboxylase (EC 6.3.4.6) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, urea, and HCO3-, whereas its 3 products are ADP, phosphate, and urea-1-carboxylate (allophanate).
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is urea:carbon-dioxide ligase (ADP-forming). Other names in common use include urease (ATP-hydrolysing), urea carboxylase (hydrolysing), ATP-urea amidolyase, urea amidolyase, UALase, and UCA. This enzyme participates in urea cycle and metabolism of amino groups. It employs one cofactor, biotin.