US Route 220
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| Route information | |
| Auxiliary route of US 20 | |
| Length: | 680 mi (1,090 km) |
| Existed: | November 11, 1926 – present |
| Major junctions | |
| South end: |
 US 1 in Rockingham, NC
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  I‑73 / I‑74 near Candor, NC  I‑85 / US 421 in Greensboro, NC I‑40 in Greensboro, NC I‑81 near Roanoke, VA  I‑64 / US 60 near Clifton Forge, VA  I-68 / US 40 in Cumberland, MD   I-70 / I-76 / Penna Turnpike near Bedford, PA I-99 from Bedford, PA to Bellefonte, PA I-80 near Bellefonte, PA   I-86 / NY 17 / Southern Tier Expressway in South Waverly, PA
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| North end: | Chemung Street in Waverly, NY |
| Location | |
| States: | North Carolina, Virginia, West Virginia, Maryland, Pennsylvania, New York |
| Highway system | |
U.S. Route 220 (US 220) is a north–south U.S. Route in the eastern United States. The highway extends for 680 miles (1,090 km) from an intersection with US 1 in Rockingham, North Carolina, to a junction with Chemung Street in Waverly, New York, just north of its interchange with New York State Route 17 (NY 17; future Interstate 86 or I-86). Some sections of the route are part of the Appalachian Development Highway System's Corridor O as well as I-73 in North Carolina. US 220 is a spur route of US 20; however, the two routes do not intersect nor do they connect via other spurs of US 20.
US 220 was assigned in 1926 as part of the establishment of the U.S. Highway System. At the time, it extended from Cumberland, Maryland, to the New York–Pennsylvania border at Lawrenceville, Pennsylvania. One year later, US 220 was realigned north of Williamsport, Pennsylvania, to connect to the New York state line at South Waverly; this supplanted most of what was originally designated U.S. Route 711. US 220 was extended south through Virginia by 1935 and to its current southern terminus by 1941.
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