U.S. Route 422 Business (Reading, Pennsylvania)
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| Route information | |
| Business route of US 422 | |
| Maintained by PennDOT | |
| Length: | 7.285 mi (11.724 km) |
| Major junctions | |
| West end: |
  US 222 / US 422 in Wyomissing
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US 422 in West Reading PA 183 in Reading   US 222 Bus. in Reading PA 562 in St. Lawrence
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| East end: |
US 422 in Reiffton
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| Location | |
| Counties: | Berks |
| Highway system | |
U.S. Route 422 Business (US 422 Bus.) is a 7.29-mile-long (11.73 km) business route of US 422 located in the Reading, Pennsylvania area. The route is one of four auxiliary routes of US 422 in Pennsylvania. Its western terminus is at an interchange with US 222 and US 422 in Wyomissing. Its eastern terminus is at an interchange with US 422 in Reiffton. US 422 Bus. heads east from US 222/US 422 along Penn Avenue, passing through Wyomissing and West Reading. The route has an interchange with the US 422 freeway before it crosses the Schuylkill River into Reading. US 422 Bus. passes through downtown Reading on the one-way pair of Franklin Street eastbound and Washington Street westbound, intersecting the southern terminus of Pennsylvania Route 183 (PA 183) and crossing US 222 Bus. The business route heads into the eastern part of the city southeast on Perkiomen Avenue before following the one-way pair of Perkiomen Avenue eastbound and Mineral Spring Road westbound into Mount Penn. US 422 Bus. continues along Perkiomen Avenue to St. Lawrence, where it intersects the western terminus of PA 562 and turns southeast. The route passes through Reiffton before it merges into eastbound US 422.
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