U.S. Route 280 in Georgia
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| Route information | |
| Auxiliary route of US 80 | |
| Maintained by ALDOT and GDOT | |
| Length: | 392 mi (631 km) |
| Major junctions | |
| West end: |
   I‑20 / I‑59 / US 31 in Birmingham, AL
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 I‑16 near Black Creek, GA
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| East end: |
   US 80 / SR 26 / SR 30 near Black Creek, GA
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| Location | |
| States: | Alabama, Georgia |
| Highway system | |
I‑459 in Hoover, AL
US 231 in Sylacauga, AL
I‑85 / US 29 / US 431 in Opelika, AL
I‑185 in Columbus, GA
US 19 in Americus, GA
I‑75 in Cordele, GA
US 23 / US 319 / US 341 / US 441 in McRae-Helena, GA
US 1 in Lyons
US 25 / US 301 in Claxton, GA
...
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