Tyrosinase-related protein 2

DCT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4HX1
Identifiers
Aliases	DCT, TRP-2, TYRP2, dopachrome tautomerase
External IDs	MGI: 102563 HomoloGene: 1447 GeneCards: DCT
Gene location (Human) Chr. Chromosome 13 (human) Band 13q32.1 Start 94,436,808 bp End 94,479,682 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 E4|14 61.6 cM Start 118,012,792 bp End 118,052,246 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • isomerase activity • metal ion binding • oxidoreductase activity • copper ion binding • dopachrome isomerase activity Cellular component • cytoplasm • integral component of membrane • cytosol • membrane • melanosome • melanosome membrane Biological process • positive regulation of neuroblast proliferation • melanin biosynthetic process • cell development • ventricular zone neuroblast division • melanin biosynthetic process from tyrosine • epidermis development • developmental pigmentation • pigmentation • metabolism • oxidation-reduction process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1638	13190
Ensembl	ENSG00000080166	ENSMUSG00000022129
UniProt	P40126	P29812
RefSeq (mRNA)	NM_001129889 NM_001922 NM_001322182 NM_001322183 NM_001322184 NM_001322185 NM_001322186	NM_010024
RefSeq (protein)	NP_001123361 NP_001309111 NP_001309112 NP_001309113 NP_001309114 NP_001309115 NP_001913	NP_034154
Location (UCSC)	Chr 13: 94.44 – 94.48 Mb	Chr 13: 118.01 – 118.05 Mb
PubMed search

4HX1

1638

13190

ENSG00000080166

ENSMUSG00000022129

P40126

P29812

NM_001322185
NM_001322186

NM_010024

NP_001309115
NP_001913

NP_034154

Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. Its expression is regulated by the microphthalmia-associated transcription factor (MITF).

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