Trypsin 1

PRSS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FXY, 1TRN, 2RA3, 4WWY, 4WXV
Identifiers
Aliases	PRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1
External IDs	MGI: 3687012 HomoloGene: 134623 GeneCards: PRSS1
Gene location (Human) Chr. Chromosome 7 (human) Band No data available Start 142,749,468 bp End 142,753,076 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band No data available Start 41,354,105 bp End 41,357,914 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • peptidase activity • serine-type endopeptidase activity • hydrolase activity • metal ion binding • serine-type peptidase activity Cellular component • extracellular region • blood microparticle • extracellular exosome • extracellular space Biological process • digestion • cobalamin metabolic process • extracellular matrix disassembly • proteolysis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5644	436522
Ensembl	ENSG00000274247 ENSG00000204983	ENSMUSG00000071521
UniProt	P07477	Q792Z1
RefSeq (mRNA)	NM_002769	NM_001038996
RefSeq (protein)	NP_002760	NP_001034085
Location (UCSC)	Chr 7: 142.75 – 142.75 Mb	Chr 7: 41.35 – 41.36 Mb
PubMed search

1FXY, 1TRN, 2RA3, 4WWY, 4WXV

5644

436522

ENSG00000274247
ENSG00000204983

ENSMUSG00000071521

P07477

Q792Z1

NM_002769

NM_001038996

NP_002760

NP_001034085

Trypsin-1, also known as cationic trypsinogen, is a protein that in humans is encoded by the PRSS1 gene. Trypsin-1 is the main isoform of trypsinogen secreted by pancreas, the others are trypsin-2 (anionic trypsinogen), and trypsin-3 (meso-trypsinogen).

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Wikipedia