Trenbolone

Trenbolone
Clinical data

AHFS/Drugs.com	International Drug Names
Pregnancy category	X
Routes of administration	Intramuscular
ATC code	none
Legal status
Legal status	CA: Schedule IV US: Schedule III
Pharmacokinetic data
Bioavailability	100% (intramuscular)
Biological half-life	48–72 hours
Excretion	Urinary
Identifiers
IUPAC name (8S,13S,14S,17S)-17-Hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one
Synonyms	Trienolone; RU-2341; Estra-4,9,11-trien-17β-ol-3-one
CAS Number	10161-33-8^N
PubChem CID	25015
ChemSpider	23383^Y
UNII	P53R4420TR
ECHA InfoCard	100.127.177
Chemical and physical data
Formula	C₁₈H₂₂O₂
Molar mass	270.37 g/mol
3D model (Jmol)	Interactive image
SMILES O=C4\C=C2/C(=C1/C=C\[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)CC4
InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3/t15-,16+,17+,18+/m1/s1^Y Key:MEHHPFQKXOUFFV-OWSLCNJRSA-N^Y
^NY (what is this?)

Trenbolone (INN, BAN), also known as trienolone or trienbolone, as well as 19-nor-δ^9,11-testosterone, Δ^9,11-nandrolone, or estra-4,9,11-trien-17β-ol-3-one, is an anabolic-androgenic steroid (AAS) of the 19-nortestosterone group. It is used in veterinary medicine in to increase muscle growth and appetite. Trenbolone is used in the form of ester prodrugs, including trenbolone acetate (brand names Revalor (in combination with estradiol), Finaplix, Finajet) and trenbolone hexahydrobenzylcarbonate (Parabolan, Hexabolan). Although it is not available as a prescription medication for humans, trenbolone enanthate (RU-1697) is sometimes sold under the nickname Trenabol.

Trenbolone improves muscle mass, feed efficiency, and mineral absorption in cattle.

It has both anabolic and androgenic effects. Once metabolized, the drugs have the effect of increasing ammonium ion uptake by muscles, leading to an increase in the rate of protein synthesis. It may also have the secondary effects of stimulating appetite and decreasing the rate of catabolism, as all anabolic steroids are believed to; however, catabolism likely increases significantly once the steroid is no longer taken. At least one study in rats has shown trenbolone to cause gene expression of the androgen receptor at least as potent as DHT. This evidence tends to indicate trenbolone can cause an increase in male secondary sex characteristics without the need to convert to dihydrotestosterone.

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