Tomoko Ohta | |
---|---|
Born | September 7, 1933 Miyoshi, Japan |
Nationality | Japanese |
Fields |
Evolutionary Biology Genetics |
Institutions |
National Institute of Genetics North Carolina State University Kihara Institute for Biological Research |
Alma mater |
North Carolina State University University of Tokyo |
Academic advisors |
Motoo Kimura Hitoshi Kihara |
Known for | development of neutral theory of molecular evolution, and nearly neutral theory |
Notable awards |
Crafoord Prize (2015) Japan Academy Prize (1985) |
Tomoko Ohta (太田 朋子 Ōta Tomoko?, born Tomoko Harada 原田 朋子 September 7, 1933, Miyoshi, Aichi) is a Japanese scientist working on population genetics/molecular evolution. She and Richard Lewontin were jointly awarded the Crafoord Prize for 2015 "for their pioneering analyses and fundamental contributions to the understanding of genetic polymorphism".
Ohta graduated from the Agriculture Department of the University of Tokyo in 1956. She worked at an editorial publishing company before she was hired at the Kihara Institute for Biological Research. There, her work focused on the cytogenetics of wheat and sugar beet. In 1962 an opportunity provided by Hitoshi Kihara to study abroad in the U.S. became available. While a graduate student at the Graduate School of North Carolina State University, she switched her graduate study focus from plant cytogenetics to population genetics with the help of her advisor, Ken-Ichi Kojima, whom she eventually became a student of. She assisted Kojima in working on problems in stochastic population genetics. She obtained her Ph.D. from North Carolina State University in 1966. Because she had studied abroad as a Fulbright student, she was only able to stay in the United States to finish her PhD.
Returning to Japan, Ohta worked under Motoo Kimura, whom was the only theoretical population geneticist in Japan at the time. After working on the neutral theory of evolution with her mentor Kimura, she became convinced that nearly neutral mutations (neither deleterious nor entirely neutral) played an important role in evolution. She developed the slightly deleterious model (Ohta, 1973), then a more general form, the nearly neutral theory of evolution. She worked at the Japanese National Institute of Genetics from 1969 to 1996, and, in 2002, she was elected to the United States National Academy of Sciences as a foreign associate in evolutionary biology.