The Tlicho Government, Tłı̨chǫ Government, Tli Cho, is a First Nations organization representing the Tłı̨chǫ Nation of the Northwest Territories, Canada that was created in 2005 when the Tłı̨chǫ Nation ratified the Tłı̨chǫ Agreement with the Government of Canada. Through this agreement certain rights relating to lands, resources and self-government were defined including Tłı̨chǫ Government ownership of "39,000 km2 of land located between Great Slave Lake and Great Bear Lake including surface and subsurface rights, the ability to define its membership known as Tłı̨chǫ citizens, jurisdiction over lands and resources in the Tłı̨chǫ traditional territory and establishment of the Wekʼèezhìı Land and Water Board and the Wekʼèezhìı Renewable Resources Board and a share of mineral royalties from the Mackenzie Valley." The word Tlı̨chǫ [tɬʰĩtʃʰõ] means Dogrib. The traditional area of the Tłı̨chǫ described by Chief Monfwi during the signing of Treaty 11 in 1921, was called Monfwı̀ Gogha Dè Nı̨htł'è [mõfwì goɣa dè nĩhtɬ'è]. Wekʼèezhìi, the management area defined by the Tłı̨chǫ Agreement, is an area larger than the land owned by the Tłı̨chǫ. Wekʼèezhìi "shares boundaries with the Sahtu Settlement Area and Nunavut, and includes the four Tłı̨chǫ member communities of Gamètì, Wekʼèezhìi, Whatì and Behchokò."
The Tłı̨chǫ Government is one of the Management Authorities of the NWT Conference of Management Authorities (CMA) for boreal caribou, along with the Government of the NWT, the Wildlife Management Advisory Council (NWT), the Gwich'in Renewable Resources Board, the Sahtu Renewable Resources Board, and the Wekʼèezhìi Renewable Resources Board.
The Tłı̨chǫ Government appoint fifty percent of the Wekʼèezhìi Renewable Resource Board, a co-management board. The other fifty percent are appointed by the Government of Canada and the Government of Northwest Territory. The WRRB is an institution of public government, responsible for managing wildlife and wildlife habitat (forests, plants and protected areas) in the Wekʼèezhìi area.