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Identifiers | |||
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54397-85-2 | |||
3D model (Jmol) | Interactive image | ||
ChEBI | CHEBI:28728 | ||
ECHA InfoCard | 100.165.003 | ||
MeSH | Thromboxane+B2 | ||
PubChem | 5283137 | ||
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Properties | |||
C20H34O6 | |||
Molar mass | 370.48 g/mol | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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what is ?) | (|||
Infobox references | |||
Thromboxane B2 is an inactive metabolite/product of thromboxane A2. It is almost completely cleared in the urine.
It itself is not involved in platelet activation and aggregation in case of a wound, but its precursor, thromboxane A2, is. Thromboxane A2 synthesis is the target of the drug aspirin, which inhibits the COX-1 enzyme (the source of thromboxane A2 in platelets).
2-(3,4-Di-hydroxyphenyl)-ethanol (DHPE) is a phenolic component of extra-virgin olive oil. An olive oil fraction containing DHPE can inhibit platelet aggregation and thromboxane B2 formation in vitro.