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Thromboxane B2

Thromboxane B2
Thromboxane B2.svg
ThromboxaneB2 spacefill.png
ThromboxaneB2.png
Identifiers
54397-85-2 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:28728 N
ECHA InfoCard 100.165.003
MeSH Thromboxane+B2
PubChem 5283137
Properties
C20H34O6
Molar mass 370.48 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Thromboxane B2 is an inactive metabolite/product of thromboxane A2. It is almost completely cleared in the urine.

It itself is not involved in platelet activation and aggregation in case of a wound, but its precursor, thromboxane A2, is. Thromboxane A2 synthesis is the target of the drug aspirin, which inhibits the COX-1 enzyme (the source of thromboxane A2 in platelets).

2-(3,4-Di-hydroxyphenyl)-ethanol (DHPE) is a phenolic component of extra-virgin olive oil. An olive oil fraction containing DHPE can inhibit platelet aggregation and thromboxane B2 formation in vitro.


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