2-(3,4-Di-hydroxyphenyl)-ethanol
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| Names | |
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IUPAC name
4-(2-Hydroxyethyl)-1,2-benzenediol
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| Other names
3-Hydroxytyrosol
3,4-dihydroxyphenylethanol (DOPET) Dihydroxyphenylethanol 2-(3,4-Di-hydroxyphenyl)-ethanol (DHPE) 3,4-dihydroxyphenolethanol (3,4-DHPEA) |
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| Identifiers | |
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3D model (JSmol)
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.114.418 |
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PubChem CID
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| UNII | |
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| Properties | |
| C8H10O3 | |
| Molar mass | 154.163193 g/mol |
| Appearance | Clear, faint yellow to yellow liquid |
| Boiling point | 174 °C (345 °F; 447 K) |
| 5 g/100 ml (25 °C) | |
| Hazards | |
| Main hazards | Causes skin irritation.
Causes serious eye irritation. May cause respiratory irritation. |
| Safety data sheet | [1] |
| R-phrases (outdated) | R36/37/38 |
| S-phrases (outdated) | S26, S37/39 |
| Related compounds | |
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Related alcohols
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ethanol, phenol, tyrosol |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 (what is   ?) |
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| Infobox references | |
Causes serious eye irritation.
May cause respiratory irritation.
Hydroxytyrosol is a phenylethanoid, a type of phenolic with antioxidant properties in vitro. In nature, hydroxytyrosol is found in olive leaf and olive oil, in the form of its elenolic acid ester oleuropein and, especially after degradation, in its plain form.
Hydroxytyrosol itself in pure form is a colorless, odorless liquid. The olives, leaves and olive pulp contain large amounts of hydroxytyrosol (compared to olive oil), most of which can be recovered to produce hydroxytyrosol extracts. However, it was found that black olives, such as common canned variety, containing iron(II) gluconate contained little hydroxytyrosol, as iron salts are catalysts for its oxidation.
Hydroxytyrosol is mentioned by the scientific committee of the European Food Safety Authority as one of several olive oil polyphenols under preliminary research for the potential to affect blood lipid levels, although there is no evidence from high-quality clinical research to indicate that this effect exists.
As of 2015, the NOAEL for hydroxytyrosol in rats is 250 mg/kg/day, with a LOAEL of 500 mg/kg/day.
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